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LOCAL NANOMECHANICAL MOTION OF THE CELL WALL OF SACCHAROMYCES CEREVISIAE                                                                           BODY ART DISEASE

2008                                                                                                                                                         06 NOVEMBER 2008
GIMZEWSKI LABORATORY
                                                                                                                                 Organized by Stephanie Adcock, the BODY
We demonstrate that the cell wall                                                                                                ART DISEASE symposium explored unique
of living Saccharomyces cerevisiae                                                                                               perspectives on the theme through
(baker’s yeast) exhibits local                                                                                                   featured presentations, exhibitions,
temperature dependent nanomechanical                                                                                             installations, workshops, round tables,
motion at characteristic frequencies.                                                                                            social gatherings and two curator talks/
The periodic motions in the range of                                                                                             tours from the vaults of the History
0.8 to 1.6 kHz with amplitudes of ~3                                                                                             and Special Collections Louise Darling
nm were measured using the cantilever                                                                                            Biomedical Library. The symposium
of an atomic force microscope (AFM).                                                                                             discussed challenging traditional
Exposure of the cells to a metabolic                                                                                             aesthetics and explored the related
inhibitor causes the periodic motion                                                                                             topics from a multitude of viewpoints.
to cease. From the strong frequency
dependence on temperature, we derive
an activation energy of 58 kJ/
mol, which is consistent with the
cell’s metabolism involving molecular
motors such as kinesin, dynein, and
myosin. The magnitude of the forces
observed (~10 nN) suggests concerted
nanomechanical activity is operative in
the cell.

ARTIST ART+ACTIVISM COLLABORATION COMMUNITY EDUCATION LECTURE PUBLICATION RESEARCH RESIDENCY ROBOTICS MIXER SYMPOSIUM ||||       ARTIST ART+ACTIVISM COLLABORATION COMMUNITY EDUCATION LECTURE PUBLICATION RESEARCH RESIDENCY ROBOTICS MIXER SYMPOSIUM ||||
     || SPRING SUMMER FALL WINTER ||||| 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 ||||| UCLA CNSI DMA BEYOND |||||  ||||| SPRING SUMMER FALL WINTER ||||| 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 ||||| UCLA CNSI DMA BEYOND ||
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