Sequencing the Human Exome: Approaches, Methodologies, and Challenges

Latest Science/AAAS Webinar

Sequence capture technology reduces the genome complexity by enriching a selective portion of the genome, targeting anywhere from 100 kb to 30 Mb of the human genome. When coupled to next generation sequencing, this technology readily facilities the resequencing of candidate genes and regions previously identified from genome wide association studies. In this webinar, our panel of experts will present their own data, defining the performance criteria necessary for using sequence capture in combination with
next generation sequencing, such as percent of target sequence detected, uniformity of coverage, and depth of coverage for variants.

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Register: www.sciencemag.org/webinar

Produced by the Science/AAAS Business Office and sponsored by Roche and 454 Sequencing